The 5th-generation iPod nano was introduced by Apple at a special event on September 9, 2009.^[1] This generation was succeeded by the 6th generation model on September 1, 2010.

It featured a larger, 56.3 mm (2.22 in.) diagonal screen (up from 50.8 mm (2.00 in.) in 3rd and 4th-generation iPod nanos), which was also wider, integrated video camera with 16 special effects, microphone, FM radio with iTunes tagging (via RDS) multiple radio regions including Americas, Asia, Australia, Europe, and Japan.^[2][3] Prices were reduced on the larger-capacity model at the time of release (the 8GB was priced at $149, and the 16GB at $179).

As well as continuing to support picture viewing and video playback, it also included Live Pause, a built-in pedometer, Nike+iPod support and a speaker.^[2] This model supported the Genius Mix feature.

The headphone jack and 30-pin dock connector swapped locations so that the headphone jack was to the left of the dock connector. Therefore, the 5th-generation iPod nano used a different Apple Universal Dock insert than the 4th-generation model.^[4]

The 5th-generation iPod nano had nine finishes: Silver, Black, Purple, Blue, Yellow, Orange, Product Red, Green and Pink. All had a glossier, shinier finish than the previous generation. Just like the 4th-generation iPod nano, the (PRODUCT)^RED and the yellow models were only available at online and retail Apple Stores.^[1][5]